Jenin, West Bank. Israel on Monday launched its most intense military operation in the occupied West Bank in nearly two decades, carrying out a series of drone strikes and sending hundreds of troops on an open-ended mission into a militant stronghold. At least eight Palestinians were killed and dozens wounded.

The crackdown was reminiscent of Israeli military tactics during the second Palestinian uprising in the early 2000s and came at a time of growing domestic pressure for a tough response to recent attacks on Israeli settlers, including a shooting last month that killed four Israelis.

The operation took place in the Jenin refugee camp — an area in the northern West Bank that has long been known as a bastion of militants. The fighting, which began shortly after midnight, continued past nightfall.

Throughout the day, black smoke rose from the crowded streets of the camp, a densely populated neighborhood that is home to some 14,000 people, while exchanges of fire rang out and drones could be heard buzzing overhead. Military bulldozers plowed through narrow streets, damaging buildings as they cleared the way for Israeli forces.

“There are bulldozers destroying the streets, snipers are inside and on roofs of houses, drones are hitting houses and Palestinians are killed in the streets,” said Jamal Huweil, a political activist in the camp, predicting the operation would fail.

The military blocked traffic in and out of Jenin, and the city resembled a ghost town. Streets were empty as armored Israeli vehicles patrolled. Piles of burning tires and garbage containers littered traffic circles. Power and water supplies were knocked out in the camp.

Palestinian youths occasionally threw stones at army vehicles before darting away.

With the sound of shooting and explosions in the background, at least 10 ambulances rushed to the overwhelmed local hospital as relatives checked to see if loved ones were inside. One ambulance arrived with a bullet hole in the front.

The Palestinians and three Arab countries with normalized ties with Israel – Jordan, Egypt and the United Arab Emirates – condemned the incursion, as did the 57-nation Organization of Islamic Cooperation.

Late Monday, the Palestinian leadership in the West Bank held an emergency meeting and said it was halting its already limited contacts with Israel. Leaders said a freeze on security coordination would remain in place, and they vowed to step up activity against Israel in the United Nations and international bodies. They also planned to minimize contact with the United States.

Israel’s prime minister, Benjamin Netanyahu, was unswayed.

“In recent months, Jenin has turned into a safe haven for terrorism. We are putting an end to this,” he said. He said the troops were destroying militant command centers and confiscating weapons supplies and factories. He claimed the operation was taking place with “minimum harm to civilians.”

Rear Adm. Daniel Hagari, the chief military spokesman, said there were a total of about 10 airstrikes — most of them aimed at keeping gunmen away from ground troops. He accused militants of operating next to a United Nations building and storing weapons inside a mosque.

He said Israel launched the operation because some 50 attacks over the past year had emanated from Jenin.

Neither the prime minister nor Hagari gave any indication of when the operation would end.